Assisted Hatching  

What Do you Understand about laser hatching?

Laser Hatching is a technique to remove the zona pellucida surrounding the embryos or blastocysts, which can be easily done by laser. The laser acts on the zona cells but leaves the embryo intact and undamaged. The zona cells are destroyed by fusing (like dissolving sugar in water), thereby allowing fertilization without needing sperm to penetrate it. This is useful where sperm has been used from frozen stored spermatozoa and hence freezing of sperm and freezing of embryos may not be available.


The viability of the embryos contains a high correlation to embryo transfer success rates. When the embryo is transferred into the uterus, it still needs time to get past the zona pellucida layer and burrow into the endometrium lining. This can take several days, and if the embryos are placed at an inappropriate time of their development (too early or too late) or inadequate conditions exist in which to implant, then the pregnancy rate may be low.

Assisted Reproduction (ART) Procedures

Intrauterine Insemination (IUI)

Intrauterine Insemination, IUI is collection of semen that are emitted during procedures other than intercourse or masturbation). The semen is directly transferred into the uterus with the help of a catheter. This treatment can be done during a natural cycle but in order to improve pregnancy rate, it is important that fertility enhancing drugs are used.

In-vitro fertilization (IVF)

In-vitro fertilization, IVF, also known as test tube baby, is the most commonly used treatment all around the world. It involves fertilization of an ovum (egg) that is exposed to around 100,000 or less sperms in a test tube for fertilization outside the body. After this, the embryo is transferred into the uterus of the female.

Intracytoplasmic Sperm Injection (ICSI)

Intracytoplasmic Sperm Injection, ICSI is done when the quality of sperm is very poor. Here the sperms are directly retrieved from the testis or epididymis. In this highly technical process a single sperm is injected into the center of an egg to make it fertile.

Surgical Sperm Retrieval

Surgical Sperm Retrieval is used in patients who face ejaculatory disorders or no sperm in the ejaculate.

Following are SSR techniques:

  • Percutaneous Epididymal Sperm Aspiration (PESA)
  • Testicular Sperm Aspiration (TESA)
  • Testicular Sperm Extraction (TESE)
  • Frozen Embryo Replacement Cycle (FERC)

In case, two or more good quality embryos are produced during the cycle, but they are not transferred, then they can be frozen for future use. They are frozen at extremely low temperature of around -180°C, so that they do not get deteriorate with time.

In this procedure, the woman has to take medicine for preparing her womb to receive these embryos. With the help of an ultrasound the lining of the uterus is determined that whether it is ready for the transfer or not.


Surrogacy is the process where the fertilized egg and sperm is placed inside the womb of another lady who will carry it till the full term of pregnancy. It is used for women with absent uterus, defective uterus, poor endometrium lining, or with repeated IVF failures.

Assisted hatching

Assisted hatching is done , hen an IVF or ICSI cycle fails. It is performed through an altercation in the outer covering of the egg either by drilling a hole through it or by thinning it. This promotes hatching or implantation of embryos, unable to escape intact from outer covering of an egg.

Donor Sperm

It is used in the cases of Azoospermia (nil sperm count), low sperm count, failure of treatment during male infertility. These sperms are obtained from healthy young men properly examined.

Donor Eggs

Many times, the egg is not of good quality that is the cause of failed treatments. Here donor eggs become the solution. These are received from a number of sources, that from professional donor, someone from the family or egg sharing. The treatment starts prior one month of the IVF cycle.

Benefits of Assisted Reproduction (ART )treatment

Assisted Reproductive Technology will benefit many previously infertile couples.

It is extremely important that a couple facing infertility problem should come forward to discuss their problem. We can arrange for Free of cost opinions from various super speciality hospitals before doctor's consultations of your query from the experts of our connected hospitals.

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